診療・研究実績について
入院患者数
2025年度は808名(※短期入院や重複した入院は除く)の患者様に当科にご入院いただいております。診断目的の精密検査、診断後の治療、合併症の管理など入院の目的は多岐に渡ります。入院を必要とした患者様の病名リストは以下の通りです。
入院患者総数 808名
| 病名 | 人数 |
| 血管炎・血管炎症候群 | 124 |
| 全身性エリテマトーデス | 64 |
| 関節リウマチ | 57 |
| 多発性筋炎/皮膚筋炎 | 53 |
| 全身性強皮症 | 34 |
| 若年性特発性関節炎 | 33 |
| 再発性多発軟骨炎 | 17 |
| シェーグレン症候群 | 14 |
| 成人スチル病 | 12 |
| IgG4関連疾患 | 11 |
| ベーチェット病 | 8 |
| リウマチ性多発筋痛症 | 6 |
| その他の膠原病・自己炎症疾患 | 12 |
| リウマチ・膠原病 | 445 |
| その他 | 363 |
外来患者数
2025年度の外来受診患者数は5,442名となっております。来院のべ人数は約30,000人程度となり、首都圏でも屈指の診療実績です。外来は平日は3つのブースで診療を行っており、午前中に初診の患者様を受け付けています。
外来受診患者数 5,442名
| 病名 | 人数 |
| 関節リウマチ | 2,058 |
| 全身性エリテマトーデス/抗リン脂質抗体症候群 | 532 |
| 血管炎症候群 | 339 |
| シェーグレン症候群 | 231 |
| 多発筋炎/皮膚筋炎 | 216 |
| 全身性強皮症 | 198 |
| 脊椎関節炎・乾癬性関節炎 | 144 |
| ベーチェット病 | 142 |
| リウマチ性多発筋痛症 | 142 |
| 再発性多発軟骨炎 | 108 |
| 若年性特発性関節炎 | 102 |
| 混合性結合組織病 | 57 |
| IgG4関連疾患 | 56 |
| 成人スチル病 | 51 |
| 自己炎症性疾患・その他の膠原病・類縁疾患 | 245 |
| リウマチ・膠原病 | 4,621 |
| その他 | 821 |
執筆について
豊富な診療経験を生かして当科スタッフが執筆を担当した書籍の一部をご紹介いたします。
2025年度
- 川畑仁人. 関節リウマチの治療 日本リウマチ学会メディカルスタッフのためのライフステージに応じた関節リウマチ患者支援ガイド2025改訂版 2025;:25-46.
- 川畑仁人. 関節リウマチの治療はどのように行うのか? 日本リウマチ学会介護・福祉スタッフのための関節リウマチQ&Aすぐわかる患者支援ガイド 2025;:4.
- 川畑仁人. IgA血管炎 免疫症候群(第3版)(Ⅰ)自己免疫疾患Ⅰ-その他の免疫疾患を含めて- 2026;:180-185.
2024年度
- 森雅亮. IV章 疾患別の最新診療指針 F.小児膠原病 総論関節リウマチ治療実践 バイブル改訂第3版 2024;:—.
- 鈴木翔太郎. 7.担がん患者の関節リウマチ あなたも名医!ピンチを乗り切る関節リウマチ診療 2024;(91):148-155.
- 森雅亮. 若年性特発性関節炎. /特集: 子どもの皮膚診療を極めるために 小児科診療 2024;1(87.春増刊号):199-205.
- 森雅亮. リウマチ・膠原病薬 新小児薬用量 改訂第10版 2024;:192-205.
- 森雅亮. 第12章リウマチ性疾患. 概説. リウマチ性疾患総論. 最新ガイドライン準拠 小児科診療・治療指針.改訂第3版. 2024;:419-420.
- 高桑由希子. CQ1 全身型若年性突発性関節炎(MAS非発症時)に対して、グルココルチコイドは有用かCQ2 全身性若年性突発性関節炎(MAS非発症時)に対して、メチルプレドニゾロンパルス療法は有用か 日本リウマチ学会 若年性突発性関節炎診療ガイドライン2024-25年版 2025;:158-162.
- 山崎和子. 全身型若年性突発性関節炎(MAS非発症時)に対して、IL-1阻害薬(カナキヌマブ、アナキンラ、リロナセプト)は有用か 日本リウマチ学会 若年性突発性関節炎診療ガイドライン2024-25年版 2025;:171-175.
- 森雅亮. 日本リウマチ学会 若年性突発性関節炎診療ガイドライン2024-25 刊行によせて 日本リウマチ学会 若年性突発性関節炎診療ガイドライン2024-25年版 2025;:ⅳ-ⅳ.
- 森雅亮. 日本リウマチ学会 若年性突発性関節炎診療ガイドライン 2024-25年版 2025;(第1):2-264.
- 元永裕生. 若年性突発性関節炎の病態生理 日本リウマチ学会 若年性突発性関節炎診療ガイドライン 2024-25年版 2025;:32-39.
- 川畑仁人. 混合性結合組織病 今日の診断指針 第9版 2025;(9):1200-1201.
- 鈴木豪. NOTE2 B型肝炎再燃のリスク評価 内科レジデント 実践マニュアル 第12版経時的流れに応じた適切な治療 2025;(12版):484-484.
- 鈴木豪. 33 膠原病、リウマチ性疾患 内科レジデント 実践マニュアル第12版経時的流れに応じた適切な治療 2025;(12版):351-360.
- 川畑仁人. 皮膚硬化および石灰化病変 膠原病診療実践バイブル 2025;:157-160.
論文掲載について
当科スタッフが中心に執筆を行った学術論文をご紹介いたします。国内・国外学会での発表も多数行っています。
2026年度(4月~7月)
① 総説又は症例解説
- 高桑由希子, 松岡伸. 肺線維症の画像診断の総論および最新の進歩. Pharma Medica, 2026;43(2):11-14.
- 川畑仁人. SLEの新規自己抗体. リウマチ科, 2026;75(6):633-638.
- 川畑仁人. 関節リウマチの臨床的寛解はどのように定義されたか. 呼吸器内科, 2026;49(6):515-521.
- 川畑仁人. 膠原病に伴う末梢神経障害-病態と臨床マネジメント. 脳神経内科, 2026;104(6):717-723.
- 山崎宜興. 膠原病に伴う間質性肺疾患の診断と治療. Medical Practice, 2026;43(8):1170-1175.
② 症例報告
- 鹿野直樹, 山﨑和子, 藤川あつ子, 林祐子, 森翔, 豊福悦史, 吉岡耕平, 山本寿子, 宮本雄策, 森雅亮, 清水直樹. 血管壁イメージングが診断と疾患活動性評価に有用であった小児原発性中枢神経血管炎. 日本小児科学会雑誌, 2026;130(6):862-869.
- 鈴木豪, 川畑仁人. 抗体結果の解釈に注意を要した関節炎先行型皮膚筋炎の一例. Medical Practice, 2026;43(8):1212-1216.
③ その他
- 川畑仁人, 加藤将, 藤井隆夫. 進行性肺線維症とは何か?-膠原病・リウマチ科の視点-. Pharma Medica, 2026;43(2):35-39.
- 川畑仁人, 鈴木勝也. 膠原病診療の進歩と実地医療における実践. Medical Practice, 2026;43(8):1081-1086.
- 川畑仁人. 臨床医が知るべき膠原病診療up to date. Medical Practice, 2026;43(8):1081.
① 原著
- Tanaka Y, Hanami K, Miyazaki Y, Ishigatsubo Y, Iwamoto T, Ushio K, Okano Y, Onobori M, Kawahata K, Saegusa J, Nakamura Y, Natsumeda M, Nozaki Y, Miyamoto T, Yamanishi Y, Ishiguro N, Kumanogoh A, Takeuchi T, Tohma S, Fujino Y, Kameda H. Real-world effectiveness, safety and patient-reported outcomes of sarilumab in patients with rheumatoid arthritis: a 52-week, prospective, open-label, non-interventional, observational, nationwide, large-cohort study in Japan (PROFILE-J). RMD open, 2026;12(2):e006446.
- Suzuki T, Yamaji M, Harada H, Kawahata K. An Exploratory Analysis of Antibody Dynamics in Isolated Organ Involvement of Antisynthetase Syndrome: A Single-Center Experience. ACR Open Rheumatology, 2026;8(6):e90079.
- Nagafuchi H, Ando T, Goto Y, Kawahata K. Clinical analysis of osteonecrosis of the jaw in patients with rheumatoid arthritis: risk factors and oral health implications. Clinical rheumatology, 2026;45(6):3227-3233.
- Yoshifuji Hajime, Uchida A. Haruhito, Onishi Yasuhiro, Miyawaki Yoshia, Amiya Eisuke, Asano Ryotaro, Hashimoto Takuya, Ishii Tomonori, Ishizaki Jun, Ito Shuichi, Iwahashi Toru, Iwata Naomi, Kiko Takatoyo, Maejima Yasuhiro, Miyamae Takako, Nagafuchi Hiroko, Shigematsu Kunihiro, Shirai Tsuyoshi, Umezawa Natsuka, Sugihara Takahiko, Watanabe Yoshiko, Tamura Naoto, Nakaoka Yoshikazu. Updated 2026 Japanese diagnostic criteria for Takayasu Arteritis. Circulation Journal, 2026;:doi: 10.1253/circj.CJ-26-0679.
- Brunner HI, Antón J, Calvo-Penadés I, Dimelow R, Horneff G, Kamphuis S, Marino R, van Maurik A, Minden K, Mori M, Ocran-Appiah J, Wilkinson C, Yamasaki Y, Assudani D; Pediatric Rheumatology Collaborative Study Group (PRCSG) and Paediatric Rheumatology International Trials Organisation (PRINTO) network investigators.. Pharmacokinetics, Pharmacodynamics, and Safety of Subcutaneous Belimumab in Pediatric Patients with Systemic Lupus Erythematosus:. Arthritis Care & Research, 2026;78(6):761-770.
2025年度
① 総説又は症例解説
- 森 雅亮. 小児川崎病治療寛解へ向けたアフェレシス. 日本アフェレシス学会誌, 2025;44(2):155-161.
- 森 雅亮. 化膿性関節炎だと思ったら少関節炎型若年性関節炎. 小児内科, 2025;57(4):562-564.
- 川畑仁人. 関節リウマチに関する最新の話題. 尿酸NEXT Stage, 2025;(2):8-9.
- 毛利万里子. Ⅱ.症例で学ぶ凝固異常症抗リン脂質抗体症候群. 小児科診療 別冊, 2025;88(6):703-707.
- 川畑仁人. 関節リウマチの鑑別と診断. Medical Practice, 2025;42(8):1154-1160.
- 川畑仁人, 松井利浩. 介護・福祉・在宅医療現場における専門医療. Pharma Medica, 2025;42(3):60-64.
- 森 雅亮.. モノクローナル抗体製剤 周産期の薬物療法 update 2025 新生児編. 周産期医学, 2025;55(9):1044-1047.
- 森 雅亮. Behcet病. 小児科診療, 2025;88(9):1211-1215.
- 高桑由希子. ANCA関連血管炎の最新アプローチ-診断・治療と今後の展望. 日本内科学会雑誌, 2025;114(10):1929-1942.
- 川畑仁人. 膠原病への最新アプローチ. 日本内科学会雑誌, 2025;114(10):1873-1875.
- 森 雅亮. 先天梅毒 病原体からみた新生児感染症感染症 臨床編-各論. 周産期医学[増刊号]周産期感染症2026, 2025;55:460-465.
- 森 雅亮. パリビズマプ・ニルセビマプ 新生児からみた周産期感染症 臨床編-総論. 周産期医学[増刊号]周産期感染症2026, 2025;55:304-308..
② その他
- 永渕裕子. 関節リウマチにより変形した関節の手術適応について. 流(ながれ), 2026;通巻(6298):23-26.
- 永渕裕子. 生物学的製剤開始前の検査と開始後の注意点について. 流(ながれ), 2026;通巻(6298):18-23.
① 原著
- Shmizu M, Kaneko S, Shimbo A, Hatano M, Miyaoka F, Irabu H, Akutsu Y, Hayashi Y, Akamine K, Mori M.. Anifrolumab for refractory cutaneous lupus lesions in pediatric systemic lupus erythematosus. Lupus., 2025;34(5):533-536.
- Kazuo Yonekura, Miya Nishio, Momoko Kashiwado, Takuya Naruto, Masaaki Mori. Prediction of the onset of the RSV epidemic with meteorological data using deep neural networks. Informatics in Medicine Unlocked, 2025;:doi.org/10.1016.
- Blockmans D, Penn SK, Setty AR, Schmidt WA, Rubbert-Roth A, Hauge EM, Keen HI, Ishii T, Khalidi N, Dejaco C, Cid MC, Hellmich B, Liu M, Zhao W, Lagunes I, Romero AB, Wung PK, Merkel PA; SELECT-GCA Study Group. A Phase 3 Trial of Upadacitinib for Giant-Cell Arteritis. The New England journal of medicine, 2025;392(20):2013-2024.
- Matsui T, Kamezaki-Nakagawa A, Hoshi M, Hirano H, Sugiyama N, Hirano T, Enami M, Toyoizumi S, Matsuyama F, Murata T, Urata Y, Kawahata K, Tohma S. Incidence and risk of malignancy in japanese patients with rheumatoid arthritis in the national database of rheumatic diseases in Japan (NinJa Database). International journal of rheumatic diseases, 2025;28(7):e70363.
- Oku K, Yamada H, Ikenoue T, Akizuki M, Hagiyama H, Ideguchi H, Ihata A, Kakutani T, Kawahata K, Matsui T, Obata J, Ohno S, Sato S, Sawa N, Suda A, Taguchi H, Takeno M, Ueda A, Yamasaki M, Yamaoka K. Vaccine-related environments and patient preferences in Japanese patients with autoimmune rheumatic diseases. Modern Rheumatology, 2025;35(6):997-1008.
- Sumitomo S, Hirano T, Moriichi A, Inoue Y, Narazaki H, Inoue M, Yokogawa N, Kambe N, Mukai T, Izawa K, Kishida D, Yoshifuji H, Yamaji K, Nishikomori R, Mori M, Miyamae T.. Consideration of useful patient-reported outcome measures to identify the unmet medical needs of children and adults with autoimmune and autoinflammatory diseases. Modern Rheumatology, 2025;35(4):599-611.
- Hayashi Y, Hatano M, Kaneko S, Shimbo A, Irabu H, Akutsu Y, Mori M, Shimizu M.. Clinical Outcomes After SARS-CoV-2 Infection and Vaccination in Patients With Pediatric Rheumatic Diseases. International Journal of Rheumatic Diseases, 2025;(8):e70394.
- Sato Toshiyuki, Sato Masaaki, Nagai Kohei, Fukasawa Masahiko, Nagashima Yoshiaki, Uchida Teisuke, Tsutiya Atsuhiro, Omoteyama Kazuki, Arito Mitsumi, Takakuwa Yukiko, Ooka Seido, Suematsu Naoya, Kawahata Kimito, Yamano Yoshihisa, Kato Tomohiro, Kurokawa Manae S.. Serum peptides as candidate biomarkers for relapsing polychondritis. Journal of mass spectrometry and advances in the clinical lab., 2025;37:28-38.
- Yuzaburo Inoue, Takayuki Kishi, Tomomi Sato, Kazuko Yamazaki, Shigeru Iwata, Asami Abe, Ken-Ei Sada, Eiichi Tanaka, Keiichiro Nishida, Atsushi Kawakami, Yutaka Kawahito, Takako Miyamae. Telemedicine for Paediatric Rheumatic Diseases in Japan: A National Survey of Physicians’ Perspectives. Modern Rheumatology, 2025;00(00):1-7.
- Tsutiya Atsuhiro, Nagai Kohei, Sato Masaaki, Omoteyama Kazuki, Sato Toshiyuki, Suematsu Naoya, Kurokawa M Suzuki, Kato Tomohiro, Arito Mitsumi.. Proximity-dependent biotin identification (BioID) screening identified novel layilin-proximal proteins. Biochemical and Biophysical Research Communications, 2025;12(779):152458.
- Omoteyama Kazuki, Sato Toshiyuki, Sato Masaaki, Tsutiya Atsuhiro, Arito Mitsumi, Kato Tomohiro, Kurokawa Manae S.. Downregulation of c-Myc expression causes accumulation of cell-surface (CS) proteins, including vimentin, via suppression of the endocytosis pathway. Biochemical and Biophysical Research Communications., 2025;25(781):152475.
- Inoue Y, Sakai R, Inoue E, Mitsunaga K, Yamaji K, Mori M, Tomiita M, Shimojo N, Miyamae T.. Nationwide epidemiological survey of primary Sjogren’s disease in Japan using the National Database of Designated Intractable Diseases. Modern Rheumatology, 2025;35(5)::859-865..
- Shimizu M, Inoue E, Sakai R, Inoue Y, Mitsunaga K, Sugihara T, Hirano T, Izawa K, Kishida D, Matsushita M, Mori M, Narazaki H, Nishikomori R, Sumitomo S, Tanaka T, Yamazaki S, Yamaji K, Yokogawa N, Yoshifuji H, Miyamae T.. Verification of unmet medical needs in patients with juvenile idiopathic arthritis in Japan. Modern Rheumatology, 2025;35(5):909-915.
- Miyamae T, Okamoto N, Inoue Y, Kubota T, Ebato T, Irabu H, Kameda H, Kaneko Y, Kubo H, Mitsunaga K, Mori M, Nakajima A, Nishimura K, Ohkubo N, Sato T, Sugita Y, Takanashi S, Tanaka T, Umebayashi H, Yashiro M, Yamanishi S, Fusama M, Hirata S, Kishimoto M, Kohno M, Kojima M, Kojima T, Morinobu A, Sugihara T, Tanaka E, Yajima N, Yanai R, Kawahito Y, Harigai M.. Recommendations for the treatment of juvenile idiopathic arthritis with oligoarthritis or polyarthritis from the 2024 update of the Japan College of Rheumatology Clinical Practice Guidelines for the management of rheumatoid arthritis including juvenile idiopathic arthritis with oligoarthritis or polyarthritis – secondary publication. Modern Rheumatology, 2025;35(5):894-908.
- Matsushita M, Sakai R, Yokogawa N, Shimizu M, Inoue Y, Inoue E, Yamaji K, Mori M, Miyamae T.. Prevalence of systemic lupus erythematosus and age-stratified treatment trends in the Japanese population: A cross-sectional study based on the National Database of Health Insurance Claims. Modern Rheumatology, 2025;35(5):850-858.
- Tamura Y, Tamura Y, Takemura R, Taniguchi Y, Tsujino I, Inami T, Matsubara H, Shigeta A, Hatano M, Adachi S, Tahara N, Sakurai K, Horimoto K, Yaoita N, Abe K, Dohi Y, Kimura K, Kubota K, Kikuchi N, Yasuoka H, Baba Y, Shinke T, Amino M, Yamaguchi N, Ikeda S, Sato T, Ishida M, Sera F, Nakanishi N, Konishi H, Kinugawa K, Kashimura T, Dohi K, Nakamura K, Usui S, Tanaka S, Kubota S, Ikeda N, Yoshikawa M, Odagiri K, Tasaka S, Takeishi Y, Sugano T, Sugimura K, Tatsumi K, Kuwana M; Japan Pulmonary Hypertension Registry Network.. Immunosuppressive Therapy for Pulmonary Arterial Hypertension Associated with Connective Tissue Diseases: Insights from Japanese Registry. Advances in therapy, 2025;42(12):6103-6117.
- Shimizu H, Furuichi M, Takeuchi N, Ito K, Funaki T, Ito Y, Mori M, Moriuchi H, Yamagishi T, Shinjoh M.. Risk factors and diagnostic indicators for congenital syphilis: a Nationwide retrospective survey. Epidemiology & Infection, 2025;153::e127-e127.
- Nagasaka K, Amano K, Nagafuchi H, Sada KE, Komagata Y, Yamamura M, Kato M, Endo T, Nakaya I, Takeuchi T, Murakawa Y, Sugihara T, Saito M, Hayashi T, Furuta S, Karasawa K, Banno S, Endo S, Majima M, Dobashi H, Kaname S, Tamura N, Arimura Y, Harigai M. Nation-wide cohort study of Japanese patients with ANCA-associated vasculitis using rituximab: effectiveness and safety after two years. Modern Rheumatology, 2025;35(6):967-973.
- Miyamae T, Sakai R, Inoue Y, Kato D, Inoue E, Hirano T, Izawa K, Kishida D, Matsushita M, Mitsunaga K, Mori M, Narazaki H, Nishikomori R, Shimizu M, Sugihara T, Sumitomo S, Tanaka T, Yamazaki S, Yamaji K, Yokogawa N, Yoshifuji H, Tanaka E, Harigai M.. Comparative clinical practice of juvenile idiopathic arthritis and rheumatoid arthritis in adolescents and young adults: A retrospective cohort study using Japanese health insurance claims data (2016-20). Modern Rheumatology, 2025;35(6):935-943..
- Nagafuchi H, Ando T, Mizushima M, Ooka S, Kawahata K. Enthesitis in patients with Behçet’s disease: A single-centre retrospective cohort study in Japan. Modern Rheumatology, 2025;35(6):1030-1034.
- Hirahara S, Katsumata Y, Sada KE, Nagafuchi H, Tanaka E, Harigai M. Health-related quality of life and work productivity in Japanese patients with primarily stable ANCA-associated vasculitis: a multicenter cross-sectional study. Modern rheumatology, 2025;35(6):974-980.
- Mori S, Shabana K, Matsui T, Nozawa T, Sugita Y, Tomiita M, Nakagishi Y, Yamasaki Y, Umebayashi H, Yashiro M, Iwata N, Yasumura J, Wakiguchi H, Yamamoto T, Takezaki S, Okura Y, Yokoyama T, Shimizu M, Hirayama M, Tohma S, Okamoto N, Mori M.. Comparison of clinical practices during the transitional and young adult phases between patients with oligoarticular/polyarticular juvenile idiopathic arthritis and those with rheumatoid arthritis in Japan. Pediatric Rheumatology, 2025;23(1):120-120.
- MotonagaYusei, Arito Mitsumi, Kawasaki Tatsuya, Yamazaki Kazuko, Mori Masaaki, Kurokawa Manae S., Kawahata Kimito, Kato Tomohiro and Ooka Seido.. Analysis of Human Leukocyte Antigen Allele Frequencies in Pediatric Patients with Arthritis and/or Enthesitis. Journal of St. Marianna University, 2025;16(2):123-133.
- Hayashi Y, Mori M, Takase H, Shimizu M.. Subcutaneous administration of methotrexate in children with paediatric rheumatic diseases. Modern Rheumatology, 2025;36(1):159-162.
- Akutsu Y, Shimbo A, Mori M, Shimizu M.. Juvenile idiopathic arthritis associated with Kabuki syndrome.:A case report. Pediatrics International, 2025;67(1):e70261..
- Kaneko S, Hatano M, Shimbo A, Miyaoka F, Irabu H, Akutsu Y, Hayashi Y, Mizuta M, Nakagishi Y, Akamine K, Iwata N, Furuno K, Tanaka T, Ueno K, Fujita S, Yokoyama K, Minato T, Izawa K, Yasumi T, Matsubayashi T, Hosoya T, Nishikawa H, Fujimura J, Asano R, Sugita Y, Watanabe K, Kobayashi A, Endo T, Eguchi K, Nishikomori R, Yasuoka R, Asano T, Kanno M, Hamada K, Fujita Y, Hayashi D, Watanabe S, Shiba T, Yasuda S, Mori M, Kanegane H, Takagi M, Shimizu M.. Serum Cytokine Profiling Differentiates Underlying Diseases in Cytokine Storm Syndrome. Arthritis & Rheumatology, 2026;78(2):463-474.
- Tada A, Otake S, Kusano T, Hoshino T, Shinjoh M, Wada T, Mori M, Moriuchi H, Ishiwada N; Japanese Severe Paediatric Group A Streptococcal Infections Study Group 8.. Clinical features and trends of severe paediatric group A streptococcal infections in Japan in the post-COVID-19 pandemic era. Epidemiology and Infection, 2026;154::e35.
- Shimizu M, Kaneko S, Shimbo A, Hatano M, Miyaoka F, Hayashi Y, Irabu H, Akutsu Y, Mori M.. Distinct expression profiles of inflammasome-associated genes in systemic juvenile idiopathic arthritis. Rheumatology (Oxford)., 2026;65(2):keaf576.
- Mori M, Leach S, Learoyd M, Vijapur D, Sadow S, Wilkins D, Abe Y, Ikeda K, Kanegane H, Kano Z, Moriuchi H, Muneuchi J, Nishikomori R, Okazaki K, Takas T, Sakaguchi A, Villafana T.. Safety and Pharmacokinetics of Nirsevimab in Japanese Infants: Primary Analysis of the Open Label JUBILUS Trial. Journal of the Pediatric Infectious Diseases Society (JPIDS), 2026;doi: 10.1093/jpids/piag008.:Epub ahead of print..
- Irabu H, Ohara A, Nakamura A, Narazaki H, Hayashi Y, Yamasaki Y, Iwata N, Ohshima S, Nishiyama S, Nakagishi Y, Fukuhara D, Ishida H, Goto M, Hashimoto K, Yasuoka R, Nozawa T, Miyamae T, Umebayashi H, Mori M, Shimizu M.. Validation of the 2019 EULAR/ACR classification criteria and clinical characteristics of childhood-onset Japanese patients with systemic lupus erythematosus. Modern Rheumatology, 2026;36(2):239-245(2):239-245.
- Matsui T, Fusama M, Kawahata K, Sakai R, Sugihara T, Tsujimura M, Matsushita I, Yajima N, Isozaki T, Shimahara N, Suzuki S, Ono R, Taguchi S, Tohma S, Yanai R, Yamazaki H, Kadonaga T, Nakabayashi H, Ando C, Kojima M, Kawahito Y. Awareness of social insurance, welfare systems, and home medical care among rheumatologists in Japan: a cross-sectional study. Modern Rheumatology, 2026;36(2):282-289.
- Matsui T, Fusama M, Kawahata K, Sakai R, Sugihara T, Tsujimura M, Matsushita I, Yajima N, Isozaki T, Shimahara N, Suzuki S, Ono R, Taguchi S, Tohma S, Yanai R, Yamazaki H, Kadonaga T, Nakabayashi H, Ando C, Kojima M, Kawahito Y. Support for patients with rheumatoid arthritis provided by care and welfare professionals in Japan: a cross-sectional study. Modern Rheumatology, 2026;36(2):218-226.
② 症例報告
- Masuda T, Suzuki T, Ohshima M, Suzuki A, Minemura N, Nakajima H. TAFRO-like Symptoms in a Sjögren’s Syndrome Patient with HTLV-1 Infection. Internal medicine (Tokyo, Japan), 2025;64(7):1107-1112.
- Tanaka M, Miyagaki T, Kubo M, Okano T, Takeuchi S, Takakuwa Y, Konishi H, Sato N, Kadono T. Two cases of lymphoma arising in immune deficiency/dysregulation presenting as primary cutaneous anaplastic large cell lymphoma during oral tacrolimus therapy. The Journal of Dermatology, 2025;52(4):e302-e303.
- Watanabe H, Ishizuka K, Hiida M, Ie K, Okuse C. Progressive Purpura in Microscopic Polyangiitis: A Case Report. CUREUS JOURNAL OF MEDICAL SCIENCE, 2025;17(9):e93569.
- Suzuki S, Takakuwa Y, Ishizaki Y, Kawasaki T, Ooka S, Kawahata K. A case of systemic lupus erythematosus complicated by TAFRO syndrome-like conditions: analysis of C-X-C motif chemokine ligand 13 and B-cell activating factor dynamics and the efficacy of combination therapy with cyclosporine and belimumab. Modern Rheumatology Case Reports, 2025;9(2):rxaf063.
2024年度
① 原著
- 福田知雄, 山上啓子, 川畑仁人, 鈴木勇三, 佐々木善浩, 宮城敬, Iris Jacobs, John-Philip Lawo, Fiona Glassman, 赤真秀人, 秀道広, 大澤勲. 日本人患者を対象とした遺伝性血管性浮腫発作の予防に対するC1-インヒビター皮下投与の有効性、薬物動態および安全性:第3相試験結果(二次出版). 新薬と臨床, 2024;73:307-333.
- 田中 敏博(JA静岡厚生連静岡厚生病院 小児科), 荒木 かほる[福岡], 岡田 雅彦, 金兼 弘和, 多屋 馨子, 塚原 宏一, 長森 恒久, 羽田 敦子, 宮田 一平, 山田 全毅, 橋本 浩一, 和田 泰三, 片寄 雅彦, 神野 俊介, 亀井 聡信, 清水 博之, 新庄 正宜, 西村 直子, 森 雅亮. 感染症診断のための核酸検査に関するアンケート調査. 小児感染免疫, 2024;36(2):183-194.
② 総説又は症例解説
- 鈴木翔太郎. 【”D2TRA”アップ・トゥ・デート ピンチを乗り切る関節リウマチ診療】(第3章)難治性関節リウマチに挑む 担がん患者の関節リウマチ. jmed mook, 2024;(91):148-155.
- 森 雅亮. 【川崎病-最近の進歩】生物学的製剤(インフリキシマブ,アナキンラを中心に). カレントテラピー, 2024;42(4):328-333.
- 川畑仁人. SLE関連自己抗体. リウマチ科, 2024;71(4):345-351.
- 鈴木翔太郎. 患者さんからよく尋ねられる内科診療のQuestion第5章 リウマチ・膠原病. 内科, 2024;133(4):770-773.
- 森 雅亮. 【子どもの皮膚診療を極めるために】皮膚症状が診断に重要な全身性疾患 若年性特発性関節炎. 小児科診療, 2024;87:199-205.
- 森 雅亮.. 小児の炎症性筋疾患. 脳と発達, 2024;56(4):295-300.
- 川畑仁人. 免疫疾患治療における新たな潮流. アレルギーの臨床, 2024;43(8):605.
- 永渕裕子. 顕微鏡的多発血管炎の最新治療. 難病と在宅ケア, 2024;30(6):32-35.
- 川畑仁人. 膠原病治療における免疫抑制薬の現状と展望. 別冊・医学のあゆみ 膠原病のすべて, 2025;2:44-50.
③ その他
- 川畑仁人. 関節リウマチ患者さんのライフステージを考えた診療を目指して. 会報かながわ, 2024;(138):6-8.
- 永渕裕子. あなたの悩みを専門医にきく 医療相談より 生物学的製剤の開始時期と開始前検査について、生物学的製剤の変更について. 機関紙 流, 2024;(383):38-43.
- 森雅亮, 川畑仁人. 内科と小児科の融合. Pharma Medica, 2024;41(2):134-137.
- 永渕裕子. 神奈川県支部の皆様へ No.9. 全国膠原病友の会神奈川県支部会報, 2024;:3-5.
- 川畑仁人. 膠原病診療の新たな潮流. Pharma Medica, 2025;42(1):7-11.
① 原著
- Yamazaki S, Shimizu M, Yakabe A, Inage E, Jimbo K, Suzuki M, Miyaoka F, Kaneko S, Irabu H, Shimbo A, Ohtomo Y, Mori M, Morio T, Shimizu T. Successful treatment with tofacitinib for anti-melanoma differentiation-associated gene 5 antibody-positive juvenile dermatomyositis: case reports and review of the literature. Immunological Medicine, 2024;47(2):110-117.
- Miyamoto T, Izawa K, Masui S, Yamazaki A, Yamasaki Y, Matsubayashi T, Shiraki M, Ohnishi H, Yasumura J, Kawabe T, Miyamae T, Matsubara T, Arakawa N, Ishige T, Takizawa T, Shimbo A, Shimizu M, Kimura N, Maeda Y, Maruyama Y, Shigemura T, Furuta J, Sato S, Tanaka H, Izumikawa M, Yamamura M, Hasegawa T, Kaneko H, Nakagishi Y, Nakano N, Iida Y, Nakamura T, Wakiguchi H, Hoshina T, Kawai T, Murakami K, Akizuki S, Morinobu A, Ohmura K, Eguchi K, Sonoda M, Ishimura M, Furuno K, Kashiwado M, Mori M, Kawahata K, Hayama K, Shimoyama K, Sasaki N, Ito T, Umebayashi H, Omori T, Nakamichi S, Dohmoto T, Hasegawa Y, Kawashima H, Watanabe S, Taguchi Y, Nakaseko H, Iwata N, Kohno H, Ando T, Ito Y, Kataoka Y, Saeki T, Kaneko U, Murase A, Hattori S, Nozawa T, Nishimura K, Nakano R, Watanabe M, Yashiro M, Nakamura T, Komai T, Kato K, Honda Y, Hiejima E, Yonezawa A, Bessho K, Okada S, Ohara O, Takita J, Yasumi T, Nishikomori R; Japan CAPS Working Group. Clinical Characteristics of Cryopyrin-Associated Periodic Syndrome and Long-Term Real-World Efficacy and Tolerability of Canakinumab in Japan: Results of a Nationwide Survey. Arthritis and rheumatology(Hoboken,N.J.), 2024;76(6)::949-962.
- Fusama M, Nakahara H, Gregg M, Kuroe Y, Urata Y, Kawahata K, Kawahito Y, Kojima M, Sugihara T, Hashimoto M, Miyamae T, Murashima A, Mori M, Yajima N, Matsui T. Challenges faced by nurses engaged in rheumatology care in Japan. Modern Rheumatology, 2024;34(4):711-719.
- Mori M.. Overview of the Treatment Goal, the Method of Evaluating Disease Activity/Physical Function, Activities of Daily Living, and Traditional Care for Systemic or Articular Juvenile Idiopathic Arthritis in Japan. Children (Basel)., 2024;11(8):952-952.
- H A Uchida, Y Nakaoka, T Sugihara, H Yoshifuji, Y Maejima, Y Watanabe, H Nagafuchi, T Okazaki, Y Komagata, Y Tanaka, E Amiya, T Atsumi, K Tanemoto, T Takeuchi,T Naniwa, A Komatsuda, H Dobashi, K Amano, N Ogawa, Y Murakawa, H Hasegawa T Hayashi, Y Arimura, M Isobe, M Harigai for Japan Research Committee of the Ministry of Health, Labour, and Welfare for Intractable Vasculitis (JPVAS). Clinical characteristics and treatment outcomes of patients with newly diagnosed Takayasu Arteritis in Japan during the first 2 years of treatment: a nationwide, retrospective cohort study. Circulation Journal, 2024;:PMID: 39261026-DOI: 10.1253/circj.CJ-24-0178.
- Mori M, Nakayama Y, Nishimata S, Yokoyama T, Matsuoka R, Hatori R, Shimizu M, Arai K, Etani Y, Sogo T, Ishizu T, Nii M, Nakashima R, Shimizu T. Efficacy and Safety of Long-Term Administration of Esomeprazole in Japanese Pediatric Patients Aged 1-14 Years with Chronic Gastric Acid-Related Disease. Pediatr Gastroenterol Hepatol Nutr., 2024;(5):274-285.
- Nakayama Y, Nagata W, Takeuchi Y, Fukui S, Fujita Y, Hosokawa Y, Ueno M, Ono K, Sumitomo S, Tabuchi Y, Nakanishi Y, Saito S, Ikeuchi H, Kawamori K, Sofue H, Doi G, Minami R, Hirota T, Minegishi K, Maeshima K, Motoyama R, Nakamura S, Suzuki S, Nishioka N, Wada TT, Onishi A, Nishimura K, Watanabe R, Yanai R, Kida T, Nishiwaki H, Yajima N, Kaneko Y, Tanaka E, Kawahito Y, Harigai M. Systematic review and meta-analysis for the 2024 update of the Japan College of Rheumatology clinical practice guidelines for the management of rheumatoid arthritis. Modern Rheumatology, 2024;34(6):1079-1094.
- Domachowske J, Hamrén UW, Banu I, Baronio R, Basavaraju B, Koen A, Leach A, Mankad VS, Pannaraj PS, Soler-Palacin P, Takas T, Mori M, Villafana T MUSIC Study Group. Safety and Pharmacokinetics of Nirsevimab in Immunocompromised Children. Pediatrics, 2024;154(4):e2024066508.
- Miyaoka F, Hatano M, Hayashi Y, Kaneko S, Shimbo A, Irabu H, Akutsu Y, Segawa Y, Mori M, Shimizu M. Atlantoaxial arthritis is more common in polyarticular JIA as compared to systemic onset JIA-Retrospective study. International Journal of Rheumatic Diseases, 2024;(11):e15396.
- Mori M, Ito Y, Ishiwada N, Ito K, Shinjoh M, Tsugawa T, Funaki T, Furuichi M, Hoshino T, Miyairi I, Kondo T, Hinoki A, Wada M, Okada K, Korematsu S, Tanuma N, Hasegawa H, Hosoi K, Yoshizaki K, Ishige M. Risks and Prevention of Severe Respiratory Syncytial Virus Infection among Infants and Children with Pulmonary Hypoplasia, Airway Stenosis, Congenital Esophageal Atresia, Inborn Errors of Metabolism, or Neuromuscular Diseases in Japan. Journal of Infection and Chemotherapy, 2024;31(3):102588.
- Fusama M, Nakahara H, Miyamae T, Mori M, Urata Y, Kawahata K, Kawahito Y, Kojima M, Sugihara T, Hashimoto M, Murashima A, Yajima N, Matsui T. Challenges nurses face in providing care for patients with juvenile idiopathic arthritis. Modern Rheumatology, 2024;35(1):185-193.
- Ishikawa T, Nishimura K, Okamoto N, Akamine K, Inoue N, Irabu H, Kato K, Keino H, Kojima M, Kubo H, Maruyama K, Mizuta M, Shabana K, Shimizu M, Sugita Y, Takakuwa Y, Takanashi S, Takase H, Umebayashi H, Umezawa N, Yamanishi S, Yamazaki K, Yashiro M, Yasumi T, Mori M.. Efficacy and safety of tumor necrosis factor inhibitors for systemic juvenile idiopathic arthritis: A systematic review. Modern Rheumatology, 2024;35(1):174-184.
- Nishimura K, Ishikawa T, Okamoto N, Akamine K, Inoue N, Irabu H, Kato K, Keino H, Kojima M, Kubo H, Maruyama K, Mizuta M, Shabana K, Shimizu M, Sugita Y, Takakuwa Y, Takanashi S, Takase H, Umebayashi H, Umezawa N, Yamanishi S, Yamazaki K, Yashiro M, Yasumi T, Mori M. Efficacy and safety of abatacept for systemic juvenile idiopathic arthritis: a systematic review. Modern Rheumatology, 2024;35(1):167-173.
- Akutsu Y, Ota M, Itamiya T, Mori M, Morio T, Yamamoto K, Okamura T, Fujio K.. Effect of Epstein-Barr Virus infection on gene regulation in immune cells of patients with Immune-Mediated Diseases. Journal of autoimmunity, 2025;:150:103355.
- Mineshita Masamichi, Nishine Hiroki, Handa Hiroshi, Inoue Takeo, Ishibashi Yuki, Kawahata Kimito, Kunishima Hiroyuki, Tsuchida Tomoya, Takemura Hiromu, Minoura Ayu, Takita Mumon, Fujitani Shigeki, the Internal Medicine COVID Management Team of St. Marianna University Hospital. 90-Day outcomes in patients with severe COVID-19 pneumonia treated with invasive mechanical ventilation. Journal of Infection Chemotherapy, 2025;31(2):102529.
- Yokogawa N, Sakai R, Matsushita M, Shimizu M, Inoue Y, Inoue E, Yamaji K, Mori M, Miyamae T. Delayed global standardization and prefectural disparities in systematic lupus erythematosus treatment in Japan: a nationwide study using the National Database of Health Insurance Claims and Specific Health Checkups of Japan. Mod Rheumatol., 2025;35(2):294-299.
- Inoue Y, Sakai R, Inoue E, Mitsunaga K, Shimizu M, Sugihara T, Matsushita M, Yamaji K, Mori M, Shimojo N, Miyamae T.. Nationwide epidemiological survey of juvenile idiopathic arthritis during transition to young adulthood in Japan using the National Database of Designated Incurable Diseases of Japan. Modern Rheumatology, 2025;35(2):359-365.
- Miyamae T, Manabe Y, Sugihara T, Umezawa N, Yoshifuji H, Tamura N, Abe Y, Furuta S, Nagafuchi H, Ishizaki J, Nakano N, Atsumi T, Karino K, Amano K, Kurasawa T, Ito S, Yoshimi R, Ogawa N, Banno S, Naniwa T, Ito S, Hara A, Hirahara S, Uchida HA, Onishi Y, Murakawa Y, Komagata Y, Nakaoka Y, Harigai M. Pregnancy and childbirth in Takayasu arteritis in Japan: A nationwide retrospective study. Pregnancy and childbirth in Takayasu arteritis in Japan: A nationwide retrospective study. Modern Rheumatology, 2025;35(2):339-344.
- Fusama M, Nakahara H, Urata Y, Kawahata K, Kawahito Y, Kojima M, Sugihara T, Hashimoto M, Miyamae T, Murashima A, Mori M, Yajima N, Matsui T. Challenges nurses face in providing care to older patients with rheumatoid arthritis: A qualitative study. Modern Rheumatology, 2025;35(2):256-264.
- Sato Masaaki, Nagai Kohei, Sato Toshiyuki, Yoshimoto Ryo, Shibano Yuto, Shibahara Minori, Satokawa Haruka, Anzai Masayuki, Uchida Teisuke, Tsutiya Atsuhiro, Takakuwa Yukiko, Omoteyama Kazuki, Arito Mitsumi, Suematsu Naoya, Ooka Seido, Kawahata Kimito, Kato Tomohiro, Kurokawa S Manae.. Aberrant oxidative modifications of neutrophil myeloperoxidase in anti-neutrophil cytoplasmic antibody-associated vasculitis. Journal of Proteomics, 2025;315:105412.
- Nagafuchi H, Ando T, Mizushima M, Ooka S, Kawahata K. Enthesitis in patients with Behçet’s disease: A single-centre retrospective cohort study in Japan. Modern Rheumatology, 2025;:doi: 10.1093/mr/roaf021.
- Matsushita M, Sakai R, Yokogawa N, Shimizu M, Inoue Y, Inoue E, Yamaji K, Mori M, Miyamae T.. Prevalence of systemic lupus erythematosus and age-stratified treatment trends in the Japanese population: a cross-sectional study based on the National Database of Health Insurance Claims. Modern Rheumatology, 2025;:Epub ahead of print.
- Ito Y, Yamagishi T, Ikenoue C, Ishiwada N, Ito K, Iwatani S, Ouchi K, Kawana K, Shimizu H, Shinjoh M, Takeuchi, Tsugawa T, Funaki T, Furuichi M, Hoshino T, Mikamo H, Miyairi I, Moriuchi H, Morioka I, Yamagishi Y, Mori M.. Clinical Practice Guidelines for the Management of Congenital Syphilis in Japan, 2023: Executive Summary. The Pediatric infectious disease journal, 2025;44(3):e90-e94.
② 症例報告
- Takakuwa Y, Ooka S, Endo N, Nakamura H, Okano T, Miyagaki T, Kadono T, Kawahata K. Long-term follow-up of vasculitis with metal allergy after cerebrovascular coil embolization. Oxford Medical Case Reports, 2025;4:208-210.

